Compile Data Set for Download or QSAR
maximum 50k data
Found 154 of kd for [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 2, MITOCHONDRIAL
having polymerids = 6577 and
complexids = 50021424,50007143
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM227589(Radicicol)
Affinity DataKd:  1.86E+4nMpH: 7.5 T: 2°CAssay Description:The PDK2 or Hsp90 N-terminal domain protein was dialyzed against 1 liter of thedialysis buffer containing 50 mM Tris-Cl, pH 7.5, 50 mM KCl, 1 mM MgCl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM81912(DC23 | Resorcinol analog, 1)
Affinity DataKd:  6.76E+3nMpH: 7.5 T: 2°CAssay Description:The PDK2 or Hsp90 N-terminal domain protein was dialyzed against 1 liter of thedialysis buffer containing 50 mM Tris-Cl, pH 7.5, 50 mM KCl, 1 mM MgCl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM227590(PA1)
Affinity DataKd:  3.57E+3nMpH: 7.5 T: 2°CAssay Description:The PDK2 or Hsp90 N-terminal domain protein was dialyzed against 1 liter of thedialysis buffer containing 50 mM Tris-Cl, pH 7.5, 50 mM KCl, 1 mM MgCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM227591(PA7)
Affinity DataKd:  1.83E+3nMpH: 7.5 T: 2°CAssay Description:The PDK2 or Hsp90 N-terminal domain protein was dialyzed against 1 liter of thedialysis buffer containing 50 mM Tris-Cl, pH 7.5, 50 mM KCl, 1 mM MgCl...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM227592(PS2)
Affinity DataKd:  711nMpH: 7.5 T: 2°CAssay Description:The PDK2 or Hsp90 N-terminal domain protein was dialyzed against 1 liter of thedialysis buffer containing 50 mM Tris-Cl, pH 7.5, 50 mM KCl, 1 mM MgCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM227593(PS8)
Affinity DataKd:  426nMpH: 7.5 T: 2°CAssay Description:The PDK2 or Hsp90 N-terminal domain protein was dialyzed against 1 liter of thedialysis buffer containing 50 mM Tris-Cl, pH 7.5, 50 mM KCl, 1 mM MgCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM227594(PS10)
Affinity DataKd:  239nMpH: 7.5 T: 2°CAssay Description:The PDK2 or Hsp90 N-terminal domain protein was dialyzed against 1 liter of thedialysis buffer containing 50 mM Tris-Cl, pH 7.5, 50 mM KCl, 1 mM MgCl...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM227593(PS8)
Affinity DataKd:  426nMAssay Description:Binding affinity to N-terminal His6-SUMO tagged recombinant human PDK2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM227594(PS10)
Affinity DataKd:  156nMAssay Description:Binding affinity to N-terminal His6-SUMO tagged recombinant human PDK2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM50232913(CHEMBL4103350)
Affinity DataKd:  22nMAssay Description:Binding affinity to N-terminal His6-SUMO tagged recombinant human PDK2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM50232905(CHEMBL4091824)
Affinity DataKd:  110nMAssay Description:Binding affinity to N-terminal His6-SUMO tagged recombinant human PDK2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414830(1-((R)-3,3,3-Trifluoro-2-hydroxy-2-methyl-propiony...)
Affinity DataKd:  130nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414831(1-((R)-3,3,3-Trifluoro-2-hydroxy-2-methyl-propiony...)
Affinity DataKd:  90nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414832(1-((R)-3,3,3-Trifluoro-2-hydroxy-2-methyl-propiony...)
Affinity DataKd:  38nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414833(1-((R)-3,3,3-Trifluoro-2-hydroxy-2-methyl-propiony...)
Affinity DataKd:  210nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414834(1-((R)-3,3,3-Trifluoro-2-hydroxy-2-methyl-propiony...)
Affinity DataKd:  190nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414836((3S,4S)—N,3-Dimethyl-N-(4-methylphenyl)-1-[(2R)-3,...)
Affinity DataKd:  31nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414838(N-(4-chlorophenyl)-N,3-dimethyl-1-[(2R)-3,3,3-trif...)
Affinity DataKd:  100nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414839((3S,4S)—N-(4-chlorophenyl)-N,3-dimethyl-1-[(2R)-3,...)
Affinity DataKd:  26nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414842((3S,4S)—N-(2-fluoro-4-methylphenyl)-N,3-dimethyl-1...)
Affinity DataKd:  14nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414843((3R,4R)—N-(2-fluoro-4-methylphenyl)-N,3-dimethyl-1...)
Affinity DataKd:  5.00E+3nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414846(4-Chloro-N-methyl-N-{1-[(2R)-3,3,3-trifluoro-2-hyd...)
Affinity DataKd:  154nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414847(N,4-Dimethyl-N-{1-[(2R)-3,3,3-trifluoro-2-hydroxy-...)
Affinity DataKd:  110nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414848(2-Fluoro-4,N-dimethyl-N-{1-[(R)-3,3,3-trifluoro-2-...)
Affinity DataKd:  69nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414849(2-Chloro-N-methyl-N-{1-[(2R)-3,3,3-trifluoro-2-hyd...)
Affinity DataKd:  53nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414851(4-Chloro-N-methyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,...)
Affinity DataKd:  57nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414853(N,4-Dimethyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,3-tri...)
Affinity DataKd:  16nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414855(2-Fluoro-N,4-dimethyl-N-[(3R,4S)-3-methyl-1-[(2R)-...)
Affinity DataKd:  13nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414856(4-Fluoro-N-methyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,...)
Affinity DataKd:  38nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414858(N-Methyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,3-trifluo...)
Affinity DataKd:  46nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414860(4-Methoxy-N-methyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3...)
Affinity DataKd:  37nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414862(2,4-Difluoro-N-methyl-N-[(3R,4S)-3-methyl-1-[(2R)-...)
Affinity DataKd:  19nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414864(3,5-Difluoro-N-methyl-N-[(3R,4S)-3-methyl-1-[(2R)-...)
Affinity DataKd:  66nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414866(4-Cyano-N-methyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,3...)
Affinity DataKd:  53nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414868(2-Fluoro-N-methyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,...)
Affinity DataKd:  35nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414870(2-Chloro-4-fluoro-N-methyl-N-[(3R,4S)-3-methyl-1-[...)
Affinity DataKd:  13nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414872(5-Fluoro-N-methyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,...)
Affinity DataKd:  51nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414874(N,1-Dimethyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,3-tri...)
Affinity DataKd:  130nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414876(4-Chloro-2-fluoro-N-methyl-N-[(3R,4S)-3-methyl-1-[...)
Affinity DataKd:  20nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414878(N-Methyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,3-trifluo...)
Affinity DataKd:  44nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414880(N-Ethyl-2-fluoro-4-methyl-N-[1-((R)-3,3,3-trifluor...)
Affinity DataKd:  69nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414881(2-Fluoro-N-isopropyl-4-methyl-N-[1-((R)-3,3,3-trif...)
Affinity DataKd:  140nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414882(4-Cyano-N-ethyl-N-[1-((R)-3,3,3-trifluoro-2-hydrox...)
Affinity DataKd:  350nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM414883(4-Cyano-N-isopropyl-N-[1-((R)-3,3,3-trifluoro-2-hy...)
Affinity DataKd:  470nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM426364(US10526325, Compound A40 | US10829489, Compound A4...)
Affinity DataKd: <300nMAssay Description:The biochemical activity assay for PDHK2 is based on the inactivation of PDC through phosphorylation by PDHK2. The assay is run in two steps: the enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM426366(US10526325, Compound A42 | US10829489, Compound A4...)
Affinity DataKd: <300nMAssay Description:The biochemical activity assay for PDHK2 is based on the inactivation of PDC through phosphorylation by PDHK2. The assay is run in two steps: the enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM426367(US10526325, Compound A43)
Affinity DataKd: <300nMAssay Description:The biochemical activity assay for PDHK2 is based on the inactivation of PDC through phosphorylation by PDHK2. The assay is run in two steps: the enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM426368(US10526325, Compound A44 | US10829489, Compound A4...)
Affinity DataKd: <300nMAssay Description:The biochemical activity assay for PDHK2 is based on the inactivation of PDC through phosphorylation by PDHK2. The assay is run in two steps: the enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM426369(US10526325, Compound A45 | US10829489, Compound A4...)
Affinity DataKd: <300nMAssay Description:The biochemical activity assay for PDHK2 is based on the inactivation of PDC through phosphorylation by PDHK2. The assay is run in two steps: the enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University of Texas Southwestern Medical Center

LigandPNGBDBM426370(US10526325, Compound A46 | US10829489, Compound A4...)
Affinity DataKd: <300nMAssay Description:The biochemical activity assay for PDHK2 is based on the inactivation of PDC through phosphorylation by PDHK2. The assay is run in two steps: the enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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